Food & Drink / Compounds / diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2)

diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2) in food: ingestion safety

Elevated risk

(People-specific data is limited; this page draws from human adult context.) Primary dietary PFAS exposure route via food packaging. Metabolizes to PFCAs in the body. Detected in blood of general population. Estrogen receptor activity in vitro.

What is dipap (polyfluoroalkyl phosphate diester, 6:2/6:2)?

The IUPAC name is bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) hydrogen phosphate.

Also known as: Bis[2-(perfluorohexyl)ethyl] Phosphate, bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) hydrogen phosphate, Bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-1-octanol) hydrogen phosphate, DTXSID50561590.

IUPAC name
bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) hydrogen phosphate
CAS number
57677-95-9
Molecular formula
C16H9F26O4P
Molecular weight
790.17 g/mol
SMILES
C(COP(=O)(O)OCCC(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F
PubChem CID
14550408

Risk for people

Elevated risk

Primary dietary PFAS exposure route via food packaging. Metabolizes to PFCAs in the body. Detected in blood of general population. Estrogen receptor activity in vitro.

Regulatory consensus

3 regulatory and scientific bodies have classified diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2). The classifications differ — that's the data.

AgencyYearClassificationNotes
FDA——FDA revoked authorization for certain PFAS in food packaging in 2024
ECHA——
Denmark——Denmark banned PFAS in food packaging in 2020

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter dipap (polyfluoroalkyl phosphate diester, 6:2/6:2)

  • Food Packaging — Fast food wrappers, Microwave popcorn bags, Pizza boxes, Bakery bags
    Dominant PFAS in food-contact paper — detected in >50% of fast food packaging
  • House Dust — Household dust, Office dust
    Dust from treated textiles and carpets contains diPAPs
  • Human Biomonitoring — General population serum, Fast food workers
    Detected in human blood — dietary exposure from food packaging is primary route

Safer alternatives

Lower-risk approaches that achieve a similar outcome to diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2):

  • Plant-based grease barriers
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: 1.2-2×
  • Wax-coated paper
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: 1.2-2×
  • Bamboo fiber packaging
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: 1.2-2×
  • Silicone-coated paper
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: 1.2-2×

Frequently asked questions

What products contain dipap (polyfluoroalkyl phosphate diester, 6:2/6:2)?

diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2) appears in: Fast food wrappers (food packaging); Microwave popcorn bags (food packaging); Household dust (house dust); Office dust (house dust); General population serum (human biomonitoring).

See diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2) in the food app

Look up products containing dipap (polyfluoroalkyl phosphate diester, 6:2/6:2), compare to alternatives, and explore the full data record.

Open in food View raw API data

Sources (1)
  1. — expert_curation

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →