Food & Drink / Compounds / Potassium chloride

Potassium chloride in food: ingestion safety

Low risk

(People-specific data is limited; this page draws from human adult context.) Potassium chloride is the most widely used potash fertilizer (60% K2O) and an essential dietary mineral. Oral LD50 rat approximately 2500 mg/kg. Generally recognized as safe (GRAS) as a food additive by FDA. GI irritant in concentrated form — nausea, vomiting, diarrhea from large oral doses. Hyperkalemia risk with rapid IV administration or renal impairment (cardiac arrhythmia, cardiac arrest). Used medically as oral supplement (Slow-K, Klor-Con) and IV fluid additive.

What is potassium chloride?

Also known as: KCl, Muriate of potash, MOP, Potash.

CAS number
7447-40-7
Molecular formula
ClK
Molecular weight
74.55 g/mol
SMILES
[Cl-].[K+]
PubChem CID
4873

Risk for people

Low risk

Potassium chloride is the most widely used potash fertilizer (60% K2O) and an essential dietary mineral. Oral LD50 rat approximately 2500 mg/kg. Generally recognized as safe (GRAS) as a food additive by FDA. GI irritant in concentrated form — nausea, vomiting, diarrhea from large oral doses. Hyperkalemia risk with rapid IV administration or renal impairment (cardiac arrhythmia, cardiac arrest). Used medically as oral supplement (Slow-K, Klor-Con) and IV fluid additive.

Regulatory consensus

2 regulatory and scientific bodies have classified Potassium chloride. The classifications differ — that's the data.

AgencyYearClassificationNotes
FDA1985GRAS (Generally Recognized as Safe) as food additive
ECHA2008Not classified as hazardous under CLP

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter potassium chloride

  • Agriculture
  • Food
  • Medicine
  • Industrial

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Potassium chloride:

  • Potassium sulfate (K2SO4)
    Trade-offs: Lower chloride content. Higher cost per unit K. Preferred for tobacco, potatoes, fruits.
    Relative cost: 2-3x KCl

Frequently asked questions

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Sources (1)

  1. IOM Dietary Reference Intakes — Potassium — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →